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Psychedelic and Dissociative Drugs - National Institute on Drug Abuse ...
Psychedelic and dissociative drugs can temporarily alter a person’s mood, thoughts, and perceptions. Among other health effects and safety concerns, people who use these substances report feeling strong emotions ranging from bliss to fear and experiencing vast changes in how they perceive reality. In recent years, there has been growing research interest in the potential of psychedelic and ...
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Psychedelic and Dissociative Drugs as Medicines
Are psychedelic or dissociative drugs already approved as medicines? Are psychedelic and dissociative drugs being studied as potential medical treatments? What is psychedelic-assisted therapy? How do “mystical experiences” affect psychedelic or dissociative drug outcomes?
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https://nida.nih.gov/research-topics/psilocybin-ma…
Psilocybin (Magic Mushrooms) | National Institute on Drug Abuse
Psilocybin is a chemical in certain types of mushrooms that grow on nearly every continent. The mushrooms have a long history of use in traditional ceremonies. Some people use them recreationally or to try to improve their mental health, although researchers still have much to learn about psilocybin’s potential uses as a medicine. Also known as shrooms or magic mushrooms, the mushrooms can ...
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https://nida.nih.gov/research-topics/mdma-ecstasy-…
MDMA (Ecstasy/Molly) - National Institute on Drug Abuse (NIDA)
MDMA, also called Molly or Ecstasy, is a lab-made (synthetic) drug that has effects similar to stimulants like methamphetamine, although some researchers and organizations consider MDMA to be a psychedelic drug because it can also mildly alter visual and time perception. MDMA’s effects may include feeling more energetic and alert and having an increased sense of well-being, warmth, and ...
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https://nida.nih.gov/research-topics/trends-statis…
Law enforcement seizures of psilocybin mushrooms rose dramatically ...
Law enforcement seizures of “magic mushrooms” or “shrooms” containing the psychoactive component psilocybin increased dramatically in the United States between January 2017 and December 2022, according to a new study funded by the National Institute on Drug Abuse, part of the National Institutes of Health. The number of law enforcement seizures increased from 402 seizures in 2017 to ...
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https://irp.nida.nih.gov/tri-feature-august-2025/
NIDA IRP Technology Resource Initiative Featured Paper
Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states Published in Science. Authors J Muir, S Lin, I K Aarrestad, H R Daniels, J Ma 1,2, L Tian, D E Olson, C K Kim Paper presented by Dr. Tarun Madangopal and selected by the NIDA TDI Paper of the Month Committee Publication Brief Description Psychedelics, a class of drugs known to act on serotonergic 5 ...
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https://nida.nih.gov/research-topics/ketamine
Ketamine | National Institute on Drug Abuse (NIDA)
Ketamine is a chemical compound used as an anesthetic in humans and animals. 1,2 It was developed decades ago as a less toxic alternative to the drug phencyclidine (PCP), which was also developed as an anesthetic. A ketamine derivative, esketamine (under the brand name Spravato ®), is approved by the U.S. Food and Drug Administration (FDA) for treatment-resistant depression in adults. There ...
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https://nida.nih.gov/news-events/news-releases/202…
Law enforcement seizures of psilocybin mushrooms rose dramatically ...
Though law enforcement seizures do not necessarily reflect prevalence of use, they represent an indicator of the availability of illicit drugs. Psilocybin mushrooms fall under a broader drug category known as psychedelic and dissociative drugs, which can temporarily alter a person’s mood, thoughts, and perceptions.
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https://nida.nih.gov/es/areas-de-investigacion/dro…
Drogas psicodélicas y disociativas - National Institute on Drug Abuse ...
Learn more about NIDA’s research on the health effects and therapeutic potential of psychedelic and dissociative drugs.
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https://nida.nih.gov/about-nida/legislative-activi…
NIDA IC Fact Sheet 2025 | National Institute on Drug Abuse
Fact sheet for the 2025 Congressional Justification.The National Institute on Drugs and Addiction¹ (NIDA) advances science on substance use and addiction to improve individual and public health. After decades of research, substance use disorder (SUD) is now understood to be a chronic, treatable brain condition. NIDA-funded research has led to effective prevention and treatment approaches ...